Potassium tert-pentyloxide, 25% w/w in toluene, Thermo Scientific Chemicals

Description

Potassium tert-pentyloxide is a strong, hindered base used in combination with lithium diisopropyl amide to generate a superbase for the selective metallation of the aralkyl system at the 6-position of protected estradiols. It is used in organic synthesis, agrochemicals, pharmaceuticals, colorants and aroma chemicals. It acts as a catalyst in polymerization and isomerizations.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Potassium tert-pentyloxide is a strong, hindered base used in combination with lithium diisopropyl amide to generate a superbase for the selective metallation of the aralkyl system at the 6-position of protected estradiols. It is used in organic synthesis, agrochemicals, pharmaceuticals, colorants and aroma chemicals. It acts as a catalyst in polymerization and isomerizations.

Notes
Air and moisture sensitive. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and acids. Reacts violently with water.

Specifications

Chemical Identifiers

• CAS: 41233-93-6
• Molecular Formula: C5H11KO
• Molecular Weight (g/mol): 126.24
• MDL Number: MFCD00064808
• InChI Key: ZRLVQFQTCMUIRM-UHFFFAOYSA-N
• Synonym: potassium 2-methylbutan-2-olate, potassium tert-amylate, potassium tert-pentoxide, potassium tert-pentylate, potassium tert-pentoxide solution, potassium 2-methyl-2-butoxide, 2-butanol, 2-methyl-, potassium salt, potassium tert-amyloxide, 2-butanol, 2-methyl-, potassium salt 1:1
• PubChem CID: 23683543
• IUPAC Name: potassium;2-methylbutan-2-olate
• SMILES: [K+].CCC(C)(C)[O-]

• Density: 0.87
• Flash Point: 4°C (39°F)
• Quantity: 250 mL
• UN Number: UN2924
• Beilstein: 4149025
• Sensitivity: Air and moisture sensitive
• Formula Weight: 126.24
• Concentration or Composition (by Analyte or Components): 25% w/w in toluene
• Chemical Name or Material: Potassium tert-pentyloxide

Safety and Handling

Product Identifier

• Potassium tert-pentyloxide, 25% w/w in toluene

Signal Word

• Danger

Hazard Category

• Aspiration toxicity Category 1
• Serious eye damage/eye irritation Category 1
• Flammable liquid Category 2
• Reproductive toxicity Category 2
• Skin corrosion/irritation Category 1 B
• Specific target organ toxicity after repeated exposure Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H304-May be fatal if swallowed and enters airways.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.
• H336-May cause drowsiness or dizziness.
• H361d-Suspected of damaging the unborn child.
• H373-May cause damage to organs.
• EUH014-Reacts violently with water.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : Toluene, Potassium tert-pentyloxide

RUO – Research Use Only