PPNDS, Tocris Bioscience™

Description

Potent and selective P2X1 antagonist

Potent and selective P2X1 receptor antagonist (pKB = 7.43 in rat vas deferens). Up to 52-fold selective over P2Y1 receptors, and selective over ecto-nucleotidase, α1A-adrenoceptors, A1, A2B, H1 and M3 receptors.

Specifications

Chemical Identifiers

• CAS: 1021868-77-8
• Molecular Formula: C18H11N4Na4O14PS2
• Molecular Weight (g/mol): 694.353
• InChI Key: TXFLDKHOZFWVAC-UHFFFAOYSA-J
• Synonym: ppnds tetrasodium
• PubChem CID: 57369378
• IUPAC Name: tetrasodium;3-[2-[4-formyl-6-methyl-5-oxo-3-(phosphonatooxymethyl)pyridin-2-ylidene]hydrazinyl]-7-nitronaphthalene-1,5-disulfonate
• SMILES: CC1=NC(=NNC2=CC(=C3C=C(C=C(C3=C2)S(=O)(=O)[O-])[N+](=O)[O-])S(=O)(=O)[O-])C(=C(C1=O)C=O)COP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+]

• Quantity: 50 mg
• Formula Weight: 694.36
• Percent Purity: >98%
• Chemical Name or Material: PPNDS