PPT, Tocris Bioscience™

Description

Subtype-selective ERα agonist

Potent, subtype-selective estrogen receptor agonist (EC50 ∽ 200 pM); displays 410-fold selectivity for ERα over ERβ. Prevents ovariectomy-induced weight gain and loss of bone mineral density, and induces gene expression in the hypothalamus following systemic administration in vivo.

Specifications

Chemical Identifiers

• CAS: 263717-53-9
• Molecular Formula: C24H22N2O3
• Molecular Weight (g/mol): 386.45
• MDL Number: MFCD03453628
• InChI Key: UOSWGERPQQOSHS-UHFFFAOYSA-N
• Synonym: ppt, 1,3,5-tris 4-hydroxyphenyl-4-propyl-1h-pyrazole, propylpyrazoletriol, propyl pyrazole triol, unii-0t83y6jzpf, 0t83y6jzpf, 4,4',4-4-propyl-1h-pyrazole-1,3,5-triyl triphenol, 1,3,5-tris 4-hydroxyphenyl-4-propylpyrazole, 4,4',4-4-propyl-1h-pyrazole-1,3,5-triyl trisphenol, 4,4',4-4-propylpyrazole-1,3,5-triyl trisphenol
• PubChem CID: 6095481
• IUPAC Name: 4-[1,5-bis(4-hydroxyphenyl)-4-propyl-2,3-dihydro-1H-pyrazol-3-ylidene]cyclohexa-2,5-dien-1-one
• SMILES: CCCC1=C(N(NC1=C1C=CC(=O)C=C1)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1

• Quantity: 10 mg
• Formula Weight: 386.45
• Percent Purity: >99%
• Chemical Name or Material: PPT