PQ 401, Tocris Bioscience™

Description

IGF1R inhibitor

Insulin-like growth factor receptor (IGF1R) inhibitor. Suppresses IGF-stimulated IGF-IR autophosphorylation with an IC50 value of 12 μM. Inhibits growth of MCF-7 breast cancer cells in vitro and in vivo.

Specifications

Chemical Identifiers

• CAS: 196868-63-0
• Molecular Formula: C18H16ClN3O2
• Molecular Weight (g/mol): 341.80
• MDL Number: MFCD00160558
• InChI Key: YBLWOZUPHDKFOT-UHFFFAOYSA-N
• Synonym: igf-1r inhibitor ii, 1-5-chloro-2-methoxyphenyl-3-2-methylquinolin-4-yl urea, unii-2n3lv83s8j, n-5-chloro-2-methoxyphenyl-n'-2-methyl-4-quinolinyl urea, n-2-methoxy-5-chlorophenyl-n′-2-methylquinolin-4-yl-urea, d0b4su, urea, n-5-chloro-2-methoxyphenyl-n'-2-methyl-4-quinolinyl, pq hplc , powder, 3-5-chloro-2-methoxyphenyl-1-2-methylquinolin-4-yl urea, n-2-methoxy-5-chlorophenyl-n'-2-methylquinolin-4-yl-urea
• PubChem CID: 9549305
• IUPAC Name: 1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
• SMILES: COC1=C(NC(=O)NC2=C3C=CC=CC3=NC(C)=C2)C=C(Cl)C=C1

• Quantity: 10 mg
• Formula Weight: 341.79
• Percent Purity: >99%
• Chemical Name or Material: PQ 401