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  6. PRE-084 hydrochloride, Tocris Bioscience™

PRE-084 hydrochloride, Tocris Bioscience™

Product Code. 30001102
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Highly selective σ1 agonist

High affinity, selective σ1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively). Selective over PCP receptors (IC50 > 100000 nM) and several other receptor systems. Produces antiamnesic and antitussive effects in vivo. Also exhibits protective effects in PC6.3 cells expressing mutant huntingtin by activating NF-κB signaling.

Chemical Identifiers

CAS 138847-85-5
Molecular Formula C19H27NO3
Molecular Weight (g/mol) 317.43
MDL Number MFCD00673883
InChI Key RQHKZUBCUZVZEF-UHFFFAOYSA-N
Synonym pre-084 hydrochloride, 2-morpholin-4-yl ethyl 1-phenylcyclohexane-1-carboxylate hydrochloride, pre-084, solid, 2-4-morpholinethyl 1-phenylcyclohexanecarboxylate hydrochloride, 2-4-morpholinethyl-1-phenylcyclohexanecarboxylate hydrochloride, 2-4-morpholinyl ethyl 1-phenylcyclohexanecarboxylate hydrochloride
PubChem CID 11314197
IUPAC Name 2-(morpholin-4-yl)ethyl 1-phenylcyclohexane-1-carboxylate
SMILES O=C(OCCN1CCOCC1)C1(CCCCC1)C1=CC=CC=C1

Specifications

Quantity 10 mg
Formula Weight 353.89
Percent Purity >99%
Chemical Name or Material PRE-084 hydrochloride
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