PROTEIN S Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA590849

Product Code. 16558021

Description

Immunogen sequence: MDINKPGPLF KPENGLLETK VYFAGFPRKV ESELIKPINP RLDGCIRSWN LMKQGASGIK EIIQEKQNKH CLVTVEKGSY YPGSGIAQFH IDYNNVSSAE GWHVNVTLNI RPSTGTGVML ALVSGNNTVP FAVSLVDSTS EKSQDILLSV ENTVIYRIQA LSLCSDQQSH LEFRVNRNNL ELSTPLKIET ISHEDLQRQL AVLDKAMKAK VATYLGGLPD VPFSATPVNA FYNGCMEVNI NGVQLDLDEA ISKHNDIRAH SCPSVWKKTK NS; Positive Samples: LO2, HeLa, 293T, Mouse liver, Mouse kidney, Rat liver, Rat kidney

Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 μg/mL, with a half-life of approximately two days. About 40% of Protein S in plasma is in a free form, whereas 60% is complexed with C4b-binding Protein (C4BP). Only the free Protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa.

Specifications

• Antigen: PROTEIN S
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PROS1
• Gene Alias: AW214361, Preproprotein S, PROS, PROS 1, PROS1, protein S, protein S (alpha), Protein S alpha, protein Sa, proteinS, PS 21, PS 22, PS 23, PS 24, PS 25, PS 26, PS21, PS22, PS23, PS24, PS25, PS26, PSA, rabbit protein S, THPH5, THPH6, unnamed protein product, vitamin K-dependent plasma protein S, vitamin K-dependent protein S, vitamin K-dependent protein S precursor
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19128, 5627, 81750
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 3.65 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
• Gene Accession No.: P07225, P53813, Q08761
• Gene Symbols: PROS1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 405-676 of human PROS1 (NP_0003042)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG