PTH1R (extracellular) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA577689

Product Code. 15924195

Description

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 μL of deionized water.

The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of JanseNULLs metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis.

Specifications

• Antigen: PTH1R (extracellular)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTH1R
• Gene Alias: PTH/PTHrP type I receptor, PTH1 receptor, PTHR, PTHR1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19228, 56813, 5745
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
• Concentration: 0.85 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P25961, P41593, Q03431
• Gene Symbols: Pth1r
• Immunogen: Peptide (C)DAVLYSGFTLDEAER, corresponding to amino acid residues 241-255 of rat Parathyroid Hormone 1 Receptor
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG