R&D Systems™ Mca-KPLGL-Dpa-AR-NH2 Fluorogenic Peptide Substrate

Substrate for MMP-1, MMP-2, MMP-7, MMP-8, MMP-9, MMP-12, MMP-13, MMP-14, MMP-15, MMP-16, ADAM10, ADAM17/TACE, Cathepsin D, and Cathepsin E

Brand:  R&D Systems™ ES010

Product Code. 18157290

Description

• The peptide substrate contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group
• Can be used to measure the activities of peptidases capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence
• Purity >95% by HPLC
• The cleavage site is the peptide bond between Gly and Leu

Specifications

• Product Type: Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2
• Storage Requirements: Samples are stable for up to twelve months from date of receipt at -20° C to -70° C. The substrate can be aliquoted and stored -20° C to -70° C in a manual defrost freezer for six months. Avoid repeated freeze-thaw cycles. Protect from exposure to direct light.