R&D Systems™ Mca-SEVNLDAEFRK(Dnp)RR-NH2 Fluorogenic Peptide Substrate

Applications: Bioactivity

Brand:  R&D Systems™ ES004

Product Code. 18196490

Description

• Contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2, 4-dinitrophenyl group
• It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence
• Purity 93.8% by HPLC
• Contains the Swedish mutation of the amyloid precursor protein (APP) beta-secretase cleavage site
• A K-R-R sequence is added for easy solubilization

Specifications

• Form: Liquid
• Format: Supplied as a stock solution in dimethyl sulfoxide (DMSO) (100μL) at a concentration of 10.0mg/mL or 4.1 mM..
• Product Type: Source: Synthetic

• For Use With (Application): Bioactivity
• Molecular Weight (g/mol): Predicted MW: 2001 Da
• Storage Requirements: Samples are stable for up to twelve months from date of receipt at -20° C to -70° C. The substrate can be aliquoted and stored -20° C to -70° C in a manual defrost freezer for six months. Avoid repeated freeze-thaw cycles. Protect from exposure to direct light