RAB3GAP1 Mouse anti-Human, Mouse, Rat, Clone: 4A3A1, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66688-1-IG-20UL

Product Code. 16828805

Description

RAB3GAP1, is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab 3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP, and is required for normal eye and brain development. Defects in Rab 3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1). WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab 3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

Specifications

• Antigen: RAB3GAP1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P69735, Q15042, Q80UJ7
• Gene Symbols: Rab3gap1
• Immunogen: RAB3GAP1 Fusion Protein Ag17710
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 4A3A1
• Conjugate: Unconjugated
• Gene: RAB3GAP1
• Gene Alias: DKFZp434A012, KIAA0066, P130, Rab3 GAP, Rab3 GAP p130, RAB3GAP, RAB3GAP1, RAB3GAP130, WARBM1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 226407, 22930, 304759
• Content And Storage: -20°C
• Form: Liquid