RAD52 Monoclonal Antibody (5E11E7), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA531888

Product Code. 16375314

Description

MA5-31888 has been tested in indirect ELISA.

DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. Double-strand breaks are generally thought to be repaired via one of two distinct mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ). Homologous recombination requires the activity of the members of the RAD52 epistasis group, which includeRAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2. RAD52 can catalyze strand annealing reactions, and can form oligomers that attach to ends of single-stranded DNA.

Specifications

• Antigen: RAD52
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: P43351
• Gene Symbols: RAD52
• Immunogen: Purified recombinant fragment of human RAD52 (AA: 269-418) expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
• Clone: 5E11E7
• Conjugate: Unconjugated
• Gene: RAD52
• Gene Alias: DNA repair protein RAD52 homolog; RAD52; RAD52 homolog (S. cerevisiae); RAD52 homolog, DNA repair protein; Rad52yh; recombination protein RAD52; rhabdomyosarcoma antigen MU-RMS-40.23
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 5893
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid