Raloxifene hydrochloride, Tocris Bioscience™

Description

Selective estrogen receptor modulator (SERM)

Selective estrogen receptor modulator (SERM) that binds to ERα and ERβ, and tissue-dependently activates or blocks estrogen-induced transcription. Acts as an antiestrogen in breast and uterine tissue, but displays estrogen agonist activity in bone. In D12 rat hypothalamic cells, inhibits progesterone receptor induction by estrogen with an IC50 of 1 nM.

Specifications

• CAS: 82640-04-8
• Molecular Formula: C28H28ClNO4S
• Quantity: 50 mg
• Synonym: raloxifene hydrochloride, raloxifene hcl, evista, keoxifene hydrochloride, 6-hydroxy-2-4-hydroxyphenyl benzo b thiophen-3-yl 4-2-piperidin-1-yl ethoxy phenyl methanone hydrochloride, keoxifene, unii-4f86w47br6, evista raloxifene hydrochloride, 6-hydroxy-2-p-hydroxyphenyl benzo b thien-3-yl-p-2-piperidinoethoxy phenyl ketone, hydrochloride
• InChI Key: BKXVVCILCIUCLG-UHFFFAOYSA-N
• SMILES: C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O.Cl
• IUPAC Name: [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone;hydrochloride
• Molecular Weight (g/mol): 510.045
• PubChem CID: 54900
• ChEBI: CHEBI:50740
• Formula Weight: 510.04
• Percent Purity: >98%
• Chemical Name or Material: Raloxifene hydrochloride