missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Rapamycin
Click to view available options
Quantity:
1 mg
Description
Rapamycin is a antifungal and immunosuppressant. Specific inhibitor of mTOR (mammalian target of Rapamycin). Complexes with FKBP-12 and binds mTOR inhibiting its activity. Inhibits interleukin-2-induced phosphorylation and activation of p70 S6 kinase. Induces autophagy in yeast and mammalian cell lines. Drives hPSC differentiation to mesendoderm and blood progenitor cells. Also used as a chemical dimerizer; rapamycin and GA3-AM (Cat. No. 5407) chemically inducible dimerization systems are orthogonal. Inhibits MERS-CoV infection of Huh7 cells in a plaque reduction assay. Enhances lentiviral transduction of hematopoietic stem cells.
![TRUSTED_SUSTAINABILITY](/content/dam/fishersci/glyphs/Sustain_Badge.png)
Specifications
Specifications
Type | Rapamycin |
CAS | 53123-88-9 |
Quantity | 1 mg |
Molecular Formula | C51H79NO13 |
Synonym | (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epepoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone |
InChI Key | QFJCIRLUMZQUOT-HPLJOQBZSA-N |
SMILES | CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC |
Molecular Weight (g/mol) | 914.187 |
PubChem CID | 5284616 |
ChEBI | CHEBI:9168 |
Show More |
Product Suggestions
Customers who viewed this item also viewed
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Rapamycin >
Spot an opportunity for improvement?Share a Content Correction