R&D Systems™ Recombinant Cynomolgus Lymphotoxin beta R/TNFRSF3 Fc, CF

Carrier-Free Recombinant Protein

Brand:  R&D Systems™ 10759-LR-050

Product Code. 18158550

Description

Measured by its ability to inhibit Lymphotoxin alpha 1/beta 2-induced IL-8 secretion in A375 human melanoma cells. Degli-Esposti, M. et al. (1997) J. Immunol. 158:1756. The ED50 for this effect is 30.0-180 ng/mL in the presence of 100 ng/mL Recombinant Human Lymphotoxin alpha 1/beta 2 (Catalog # 8884-LY ).

Specifications

• Accession Number: XP_005569951.1
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Molecular Weight (g/mol): M.W. (Observed): 57-68 kDa, under reducing conditions, M.W. (Theoretical): 48 kDa
• Source: Chinese Hamster Ovary cell line, CHO-derived cynomolgus monkey Lymphotoxin beta R/TNFRSF3 protein Cynomolgus Monkey Lymphotoxin beta R/TNFRSF3 (Ser28-Met227) (N-terminus) Accession # XP_005569951.1 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Endotoxin Concentration: <0.10 EU per 1 μg of the protein by the LAL method.
• Conjugate: Unconjugated
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.

• For Use With (Application): Bioactivity
• Gene ID (Entrez): 4055
• Quantity: 50 μg
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Gene Alias: CD18, D12S370, ltbetar, LT-BETA-R, LTBR, lymphotoxin B receptor, lymphotoxin beta receptor (TNFR superfamily, member 3), Lymphotoxin-beta receptor, LymphotoxinbR, TNF RIII, TNF Rrp, TNFCRTNF-RIII, TNFR superfamily, member 3, TNFR2-RP, TNFR3, TNF-R-III, TNFR-RP, TNFRSF3, TNFRSF3TNFR-III, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, tumor necrosis factor receptor superfamily member 3, tumor necrosis factor receptor superfamily, member 3, Tumor necrosis factor receptor type III
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Protein: Lymphotoxin beta R/TNFRSF3