R&D Systems™ Recombinant Cynomolgus/Rhesus Macaque TrkA His Protein

Brand:  R&D Systems™ 11317-TK-050

Product Code. 18706936

Description

Measured by its ability to inhibit NGF-induced proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is 0.0800-0.800 μg/mL in the presence of 10 ng/mL of Recombinant Human beta-NGF Protein (Catalog # 256-GF ).

Specifications

• Accession Number: XP_005541454.3
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Molecular Weight (g/mol): M.W. Observed: 75-90 kDa, under reducing conditions., M.W. Theoretical: 43 kDa
• Source: Chinese Hamster Ovary cell line, CHO-derived TrkA protein Ser34-Gly423, with a C-terminal 6-His tag
• Endotoxin Concentration: <0.10 EU per 1 μg of the protein by the LAL method.
• Conjugate: Unconjugated
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

• For Use With (Application): Bioactivity
• Gene ID (Entrez): 4914
• Quantity: 50 μg
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Gene Alias: DKFZp781I14186, EC 2.7.10, EC 2.7.10.1, MTChigh affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase, receptor, type 1, NTRK1, NTRK-1, p140-TrkA, TRK1-transforming tyrosine kinase protein, Trk-A, TRKAOncogene TRK, TRKTRK1, tyrosine kinase receptor A
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Protein: TrkA