R&D Systems™ Recombinant Human IL-22 (HEK293-expressed) Protein

Brand:  R&D Systems™ 11311-IL-01M

Product Code. 18759706

Description

Measured by its ability to induce IL-10 secretion in COLO 205 human colorectal adenocarcinoma cells. Nagalakshmi, M.L. et al. (2004) International Immunopharmacology 4:679. The ED50 for this effect is 0.160-1.60 ng/mL.

Specifications

• Accession Number: Q9GZX6.1
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Molecular Weight (g/mol): M.W. Observed: 28-32 kDa, under reducing conditions., M.W. Theoretical: 17 kDa
• Source: Human embryonic kidney cell, HEK293-derived human IL-22 protein Ala34-Ile179
• Endotoxin Concentration: <0.10 EU per 1μg of the protein by the LAL method.
• Conjugate: Unconjugated
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.

• For Use With (Application): Bioactivity
• Gene ID (Entrez): 50616
• Quantity: 1 mg
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Gene Alias: Cytokine Zcyto18, IL-10-related T-cell-derived inducible factor, IL22, IL-D110, IL-TIF, ILTIFIL-10-related T-cell-derived-inducible factor, IL-TIFMGC79382, interleukin 22, interleukin-22, MGC79384, TIFa, TIFIL-23, zcyto18
• Reconstitution: Reconstitute the 10 μg size at 100 μg/mL in PBS. Reconstitute all other sizes at 500 μg/mL in PBS.
• Protein: IL-22