R&D Systems™ Recombinant Human/Mouse/Rat BMP-2 Protein

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Brand:  R&D Systems™ 355-BM-500/CF

Product Code. 18644749

Description

Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Binnerts, M.E. et al. (2004) Biochem. Biophys. Res. Commun. 315(2):272. The ED50 for this effect is 40-200 ng/mL.

Specifications

• Accession Number: P12643
• Formulation: Lyophilized from a 0.2 μm filtered solution in Glycine, Sucrose, Tween™ 80 and Glutamic Acid.
• Molecular Weight (g/mol): 13 kDa (monomer)
• Quantity: 500 μg
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Structural Form: Disulfide-linked homodimer
• Gene Alias: BDA2, BMP2, BMP-2, BMP-2A, BMP2ABone morphogenetic protein 2A, bone morphogenetic protein 2, SSFSC
• Conjugate: Unconjugated
• Species: Human, Mouse, Rat
• Reconstitution: Reconstitute at 100 to 200 μg/mL in sterile 4 mM HCI.

• For Use With (Application): Bioactivity
• Gene ID (Entrez): 650
• Name: BMP-2
• Source: Chinese Hamster Ovary cell line,CHO-derived BMP-2 protein Gln283-Arg396
• Regulatory Status: RUO
• Endotoxin Concentration: <0.10 EU per 1 μg of the protein by the LAL method.
• Gene Symbol: BMP2
• Cross Reactivity: BMP-2
• Recombinant: Recombinant
• Purity or Quality Grade: 95%, by SDS-PAGE under reducing conditions and visualized by silver stain.