R&D Systems™ Recombinant Human VISTA/B7-H5/PD-1H Fc Chimera Protein

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Brand:  R&D Systems™ 7126-B7-050

Product Code. 18337417

Description

Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is 1-6 μg/mL.

Specifications

• Accession Number: AAH20568
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Molecular Weight (g/mol): M.W. (Observed): 64-75 kDa, reducing conditions; M.W. (theoretical): 44.8 kDa (monomer)
• Quantity: 50 μg
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.01 EU / 1 μg of the protein by the LAL method.
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 200 μg/mL in PBS.
• Protein: VISTA/B7-H5/PD-1 H

• For Use With (Application): Bioactivity
• Gene ID (Entrez): 64115
• Name: Gi24/VISTA/B7-H5 Fc Chimera
• Source: Mouse myeloma cell line, NS0-derived human VISTA/B7-H5/PD-1 H protein Human VISTA/B7-H5/PD-1 H (Phe33-Ala194) (N-terminus) Accession # AAH20568 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Structural Form: Disufide-linked homodimer
• Gene Symbol: C10orf54
• Recombinant: Recombinant
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.