Rivastigmine tartrate, Tocris Bioscience™

Description

Dual AChE and BChE inhibitor

Rivastigmine tartrate is a cholinesterase inhibitor; inhibits both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50 ranges are 4.3-4760 nM and 16-238 nM respectively). Rivastigmine increases α-secretase activity and directs APP processing to the non-amyloidogenic pathway. Brain penetrant.

Specifications

• CAS: 129101-54-8
• Molecular Formula: C18H28N2O8
• MDL Number: MFCD03700731
• Quantity: 50 mg
• Synonym: rivastigmine tartrate, rivastigmine bitartrate, sdz-ena 713, rivastigmine hydrogen tartrate, rivastigmine hydrogentartrate, unii-9iy2357jpe, s-3-1-dimethylamino ethyl phenyl ethyl methyl carbamate 2r,3r-2,3-dihydroxysuccinate, rivastigmine tartrate exelon, carbamic acid, ethylmethyl-, 3-1s-1-dimethylamino ethyl phenyl ester, 2r,3r-2,3-dihydroxybutanedioate 1:1
• InChI Key: GWHQHAUAXRMMOT-RWALOXMOSA-N
• SMILES: O[C@@H]([C@H](O)C(O)=O)C(O)=O.CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C
• IUPAC Name: (2S,3S)-2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate
• Molecular Weight (g/mol): 400.43
• PubChem CID: 6918078
• ChEBI: CHEBI:64358
• Formula Weight: 400.42
• Percent Purity: >99%
• Chemical Name or Material: Rivastigmine tartrate