RNASEL Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 22577-1-AP-150UL

Product Code. 16841985

Description

A virally induced endoribonuclease, RNase L is the terminal factor of the anti-viral action of interferon. Activation of RNase L results in inhibition of viral proliferation. Activation of RNase L has also been determined to degrade RNA, thus, initiating a cellular stress response, inducing apoptosis. Since mutations in RNase L relate to an increased incidence of prostate cancer, the activation of RNase L functions in counteracting prostate cancer, via apoptosis.

Specifications

• Antigen: RNASEL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RNASEL
• Gene Alias: 2 5A dependent ribonuclease, 2 5A dependent RNase, PRCA1, Ribonuclease 4, Ribonuclease L, RNase L, RNASEL, RNS4
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 24014, 359726, 6041
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.29 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q05823, Q05921
• Gene Symbols: Rnasel
• Immunogen: RNASEL Fusion Protein Ag17409
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG