missing translation for 'onlineSavingsMsg'
Learn More
Learn More
RRAD Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA539199
This item is not returnable.
View return policy
Description
The Ras-encoded family of proteins bind GDP and GTP with high affinity. They possess a low level of intrinsic GTPase activity that increases more than 100-fold when interacting with cytosolic GTPase activating protein (GAP). Ras family members include H-Ras, K-Ras, N-Ras, M-Ras, R-Ras, ERas, Rheb, TC 21, RASL11B and Rad (Ras associated with diabetes) GTPase.Rad GTPase is a GTP-binding protein that is similar to Ras but has unique features. Unlike other small GTPases, Rad GTPase lacks typical pren-ylation motifs at its C terminus. The Rad GTPase enzyme binds calmodulin, inhibits vascular lesion formation, has low intrinsic GTPase activity and cannot be stimulated by any known GAP molecules. Rad GTPase is expressed in skeletal muscle, cardiac muscle and lung tissues and is overexpressed in the skeletal muscle tissue of individuals with type II diabetes.Specifications
RRAD | |
Polyclonal | |
Unconjugated | |
RRAD | |
Ras-related associated with diabetes, RAD, REM3, GTP-binding protein RAD, RAS, RAD and GEM like GTP binding 3, ras associated with diabetes | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
56437, 6236, 83521 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P55042, O88667, P55043 | |
RRAD | |
A synthetic peptide derived from the internal region of human RAD | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |