RS 127445 hydrochloride, Tocris Bioscience™

Description

High affinity and selective 5-HT2B antagonist

High affinity 5-HT2B receptor antagonist (pKi = 9.5). Displays 1000-fold selectivity for 5-HT2B with good bioavailability.

Specifications

Chemical Identifiers

• CAS: 199864-86-3
• Molecular Formula: C17H17ClFN3
• Molecular Weight (g/mol): 317.79
• MDL Number: MFCD11112196
• InChI Key: MKJPYBJBPRFMHL-UHFFFAOYSA-N
• Synonym: 4-4-fluoronaphthalen-1-yl-6-isopropylpyrimidin-2-amine hydrochloride, rs-127445 hydrochloride, 4-4-fluoro-1-naphthalenyl-6-1-methylethyl-2-pyrimidinamine hydrochloride, rs 127445 hydrochloride, 2-amino-4-4-fluoronaphth-1-yl-6-isopropylpyrimidine hydrochloride, mt 500 hydrochloride, rs127445 hydrochloride, rs-127445 hydrochloride hplc , powder, 2-amino-4-4-fluoronaphth-1-yl-6-isopropylpyrimidine monohydrochloride, 4-4-fluoronaphthalen-1-yl-6-isopropylpyrimidin-2-aminehydrochloride
• PubChem CID: 9905058
• IUPAC Name: 4-(4-fluoronaphthalen-1-yl)-6-(propan-2-yl)pyrimidin-2-amine hydrochloride
• SMILES: Cl.CC(C)C1=NC(N)=NC(=C1)C1=C2C=CC=CC2=C(F)C=C1

• Quantity: 10 mg
• Formula Weight: 317.79
• Percent Purity: >98%
• Chemical Name or Material: RS 127445 hydrochloride