RU 28318, potassium salt, Tocris Bioscience™

Description

Potent, selective mineralocorticoid receptor antagonist

Potent and selective antagonist for the mineralocorticoid receptor (MR). Inhibits aldosterone production and secretion, and selectively decreases ex-vivo MR binding in the hippocampus of adrenalectomised rats. Also decreases blood pressure in female rats following central administration in vivo.

Specifications

Chemical Identifiers

• CAS: 76676-34-1
• Molecular Formula: C25H37KO4
• Molecular Weight (g/mol): 440.665
• InChI Key: HXJITUGMCJCKCE-UYOQDFFISA-M
• Synonym: 7a,17a-17-hydroxy-3-oxo-7-propylpregn-4-ene-21-carboxylic acid, potassium salt
• PubChem CID: 23677972
• IUPAC Name: potassium;3-[(7R,8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-7-propyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate
• SMILES: CCCC1CC2=CC(=O)CCC2(C3C1C4CCC(C4(CC3)C)(CCC(=O)[O-])O)C.[K+]

• Quantity: 50 mg
• Formula Weight: 440.66
• Percent Purity: >98%
• Chemical Name or Material: RU 28318, potassium salt