(S)-(-)-4-Benzyl-2-oxazolidinone, 99%, Thermo Scientific Chemicals

Description

(S)-(-)-4-Benzyl-2-oxazolidinone is used in chiral auxiliary asymmetric alkylation. It has been used in the synthesis of (S)-equol. Preparation and functionalization of chiral, stabilized ylides. It was used for asymmetric synthesis of (3R)- and (3S)-piperazic acid.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(S)-(-)-4-Benzyl-2-oxazolidinone is used in chiral auxiliary asymmetric alkylation. It has been used in the synthesis of (S)-equol. Preparation and functionalization of chiral, stabilized ylides. It was used for asymmetric synthesis of (3R)- and (3S)-piperazic acid.

Solubility
Insoluble in water.

Notes
Hygroscopic. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 90719-32-7
• Molecular Formula: C10H11NO2
• Molecular Weight (g/mol): 177.20
• MDL Number: MFCD00064496
• InChI Key: OJOFMLDBXPDXLQ-VIFPVBQESA-N
• Synonym: s-4-benzyl-2-oxazolidinone, s-4-benzyloxazolidin-2-one, 4s-4-benzyl-1,3-oxazolidin-2-one, s---4-benzyl-2-oxazolidinone, s-4-benzyl-oxazolidin-2-one, 2-oxazolidinone, 4-phenylmethyl-, 4s, s-+-4-benzyl-2-oxazolidinone, s-4-phenylmethyl-2-oxazolidinone, 4s-4-phenylmethyl-1,3-oxazolidin-2-one
• PubChem CID: 736225
• IUPAC Name: (4S)-4-benzyl-1,3-oxazolidin-2-one
• SMILES: O=C1N[C@@H](CC2=CC=CC=C2)CO1

• Melting Point: 87°C to 89°C
• Beilstein: 3649667
• Solubility Information: Insoluble in water.
• Quantity: 25 g
• Formula Weight: 177.2
• Optical Rotation: −64° (c=1 in Chloroform)
• Sensitivity: Hygroscopic
• Percent Purity: 99%
• Chemical Name or Material: (S)-(-)-4-Benzyl-2-oxazolidinone

Safety and Handling

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Specific target organ toxicity after repeated exposure Category 2

Hazard Statement

• H302-Harmful if swallowed.
• H373-May cause damage to organs.

Precautionary Statement

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P264-Wash thoroughly after handling.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

RUO – Research Use Only