(S)-(+)-Ibuprofen, 99%, Thermo Scientific Chemicals

Description

(S)-(+)-Ibuprofen, CAS # 51146-56-6, is the active enantomerof the non-steroidal anti-inflammatory drug, ibuprofen.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Ibuprofen is a nonsteroidal anti-inflammatory drug commonly used in its racemic form

(S)-(+)-Ibuprofen is the active enantiomer of this drug that confers anti-inflammatory activity

(S)-(+)-Ibuprofen inhibits prostaglandin synthesis and thus reduces inflammation and pain when ingested

Applications

As the active enantiomer of ibuprofen, (S)-(+)-Ibuprofen is used in laboratory research for pharmacokinetic studies

(S)-(+)-Ibuprofen may be used as an inhibitor of cycloogenase 1 and 2 and an agonist of PPARalpha and PPARgamma

(S)-(+)-Ibuprofen may be used as material to study development of drug delivery systems

Specifications

Chemical Identifiers

• CAS: 51146-56-6
• Molecular Formula: C₁₃H₁₈O₂
• Molecular Weight (g/mol): 206.28
• MDL Number: MFCD00069289
• InChI Key: HEFNNWSXXWATRW-JTQLQIEISA-N
• Synonym: s-+-ibuprofen, dexibuprofen, s +-ibuprofen, s-2-4-isobutylphenyl propanoic acid, s-ibuprofen, d-ibuproten, s-+-2-4-isobutylphenyl propionic acid, s-+-4-isobutyl-alpha-methylphenylacetic acid, +-s-p-isobutylhydratropic acid, seractil
• PubChem CID: 39912
• ChEBI: CHEBI:43415
• IUPAC Name: (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid
• SMILES: CC(C)CC1=CC=C(C=C1)C(C)C(=O)O

• CAS Min %: 98.5
• CAS Max %: 100.0
• Melting Point: 49.0°C to 53.0°C
• Color: White
• Flash Point: 113°C
• Infrared Spectrum: Authentic
• Assay Percent Range: 98.5% min. (GC)
• Packaging: Glass bottle
• Quantity: 5 g
• Specific Rotation Condition: + 57.00 (20.00°C c=2,EtOH)
• Specific Rotation: + 57.00
• Solubility Information: Solubility in water: insoluble. Other solubilities: readily soluble in most organic solvents
• Formula Weight: 206.28
• Percent Purity: 99%
• Physical Form: Crystalline Powder or Crystals
• Chemical Name or Material: (S)-(+)-Ibuprofen, 99%

Safety and Handling

Product Identifier

• (S)-(+)-Ibuprofen

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H302-Harmful if swallowed.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

Supplemental information

• MIXTURE LIST-Contains : (S)-(+)-Ibuprofen

RUO – Research Use Only