(S)-(-)-Nicotine, 99%, Thermo Scientific Chemicals

Description

L-Nicotine, CAS # 54-11-5, has been shown in laboratory studies to alleviate smoking habits. It is also known as 3-(1-methyl-2-pyrrolidinyl)pyridine or (S)-(-)-nicotine.

(S)-(-)-Nicotine is utilized as a therapeutic agent to eliminate smoking with the damage it does to health. It is widely used as a drug to enhance the memory or other cognition functions, which is second to caffeine. Lesser levels of nicotine given in the form of gum, may help to eliminate smoking.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• L-Nicotine is a naturally occuring alkaloid in the nightshade family of plants
• It is also known as 3-(1-methyl-2-pyrrolidinyl)pyridine or (S)-(-)-nicotine
Applications
• L-Nicotine has been shown in studies to alleviate smoking habits
• It has also been shown to enhance cognitive functions such as memory
• Studies show that lower levels of nicotine in the form of gum may also help eliminate smoking habits

Specifications

Chemical Identifiers

• CAS: 54-11-5
• Molecular Formula: C10H14N2
• MDL Number: MFCD00006369
• InChI Key: SNICXCGAKADSCV-JTQLQIEISA-N
• Synonym: nicotine, l-nicotine, --nicotine, s-nicotine, habitrol, s-3-1-methylpyrrolidin-2-yl pyridine, nicoderm, nicotrol, s---nicotine, nicoderm cq
• PubChem CID: 89594
• ChEBI: CHEBI:17688
• IUPAC Name: 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine

• Melting Point: -79°C
• Density: 1.017
• pH: 10.2
• Boiling Point: 245°C to 248°C
• Flash Point: 101°C (213°F)
• Assay Percent Range: 99%
• Odor: Characteristic
• Refractive Index: 1.5265
• Quantity: 100 g
• UN Number: UN1654
• Beilstein: 82109
• Sensitivity: Air and light sensitive; Hygroscopic
• Merck Index: 14,6524
• Solubility Information: Miscible with water,alcohol,ether and light petroleum.
• Optical Rotation: −168° (neat)
• SMILES: CN1CCCC1C2=CN=CC=C2
• Molecular Weight (g/mol): 162.236
• Formula Weight: 162.24
• Percent Purity: 99%
• Physical Form: Liquid
• Chemical Name or Material: (S)- (-)-Nicotine

Safety and Handling

Product Identifier

• (S)-(-)-Nicotine

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 2
• LONG-TERM AQUATIC HAZARD Chronic 2

Hazard Statement

• H300-Fatal if swallowed.
• H310-Fatal in contact with skin.
• H330-Fatal if inhaled.
• H411-Toxic to aquatic life with long lasting effects.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P310-Immediately call a POISON CENTER/doctor/.
• P330-Rinse mouth.
• P361-Take off immediately all contaminated clothing.

Supplemental information

• MIXTURE LIST-Contains : Nicotine

RUO – Research Use Only