SB 366791, Tocris Bioscience™

Description

Potent, selective, competitive TRPV1 antagonist

Potent, selective and competitive vanilloid TRPV1 receptor antagonist (pA2 = 7.71 at hVR1); antagonizes hTRPV1 receptors activated by agonists, noxious heat, but not protons. Displays selectivity over a wide range of receptors and systems including CB1 and CB2 receptors, voltage-gated Ca2+ channels and the hyperpolarization-activated current (Ih).

Specifications

Chemical Identifiers

• CAS: 472981-92-3
• Molecular Formula: C16H14ClNO2
• Molecular Weight (g/mol): 287.743
• InChI Key: RYAMDQKWNKKFHD-JXMROGBWSA-N
• Synonym: 2e-3-4-chlorophenyl-n-3-methoxyphenyl prop-2-enamide, n-3-methoxyphenyl-4-chlorocinnamide, n-3-methoxyphenyl-4-chlorocinnamanilide, e-3-4-chlorophenyl-n-3-methoxyphenyl acrylamide, ftalidap 27, 3-4-chlorophenyl-n-3-methoxyphenyl prop-2-enamide, 2-propenamide, 3-4-chlorophenyl-n-3-methoxyphenyl, sb hplc , powder, e-3-4-chlorophenyl-n-3-methoxyphenyl prop-2-enamide
• PubChem CID: 667594
• IUPAC Name: (E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-enamide
• SMILES: COC1=CC=CC(=C1)NC(=O)C=CC2=CC=C(C=C2)Cl

• Quantity: 10 mg
• Formula Weight: 287.75
• Percent Purity: >99%
• Chemical Name or Material: SB 366791