Tocris™ SB 4

Potent BMP4 agonist

Brand:  Tocris™ 6881/50

Product Code. 18759586

Description

SB 4 is a potent BMP4 agonist (EC50 = 74 nM). Activates canonical BMP signaling and increases SMAD-1/5/9 phosphorylation, with no effect on p-SMAD-2, p-SMAD-3 or p-TAK1. Bypasses noggin-induced inhibition of type I BMP receptors.

Specifications

• Chemical Name or Material: 2-[[(4-Bromophenyl)methyl]thio]benzoxazole
• Quantity: 50 mg
• Formula Weight: 320.2
• Purity: 99%

• CAS: 100874-08-6
• Molecular Formula: C₁₄H₁₀BrNOS
• Product Type: Agonist