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  8. SC 26196, Tocris Bioscience™

SC 26196, Tocris Bioscience™

Product Code. 18075742
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Selective fatty acid desaturase 2 inhibitor

Selective fatty acid desaturase 2 (FADS2, also known as Δ6 desaturase) inhibitor (IC50 = 0.2 μM in vitro). Displays selectivity over FADS1 and stearoly-CoA 9-desaturase (Δ5 desaturase and SCD-1/Δ9 desaturase, respectively) (IC50 values are >200 μM in vitro). Exhibits anti-inflammatory properties in a mouse edema model. Eliminates CSCs from ovarian cancer cell lines and inhibits sphere formation in vitro.

Chemical Identifiers

CAS 218136-59-5
Molecular Formula C27H29N5
Molecular Weight (g/mol) 423.564
InChI Key QFYKXKMYVYOUNJ-UHFFFAOYSA-N
Synonym α, α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile
PubChem CID 71752132
IUPAC Name 2,2-diphenyl-5-[4-(pyridin-3-ylmethylideneamino)piperazin-1-yl]pentanenitrile
SMILES C1CN(CCN1CCCC(C#N)(C2=CC=CC=C2)C3=CC=CC=C3)N=CC4=CN=CC=C4

Specifications

Quantity 50 mg
Formula Weight 423.55
Percent Purity >98%
Chemical Name or Material SC 26196
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