SCH 50911, Tocris Bioscience™

Description

Selective and competitive GABAB antagonist; orally bioavailable

A selective, competitive and orally active GABAB antagonist. Displays an IC50 of 1.1 μM at GABAB, approximately 60 times that of CGP 35348 (Cat. No. 1245) and no binding affinity for GABAA at concentrations up to 100 μM.

Specifications

Chemical Identifiers

• CAS: 733717-87-8
• Molecular Formula: C8H15NO3
• Molecular Weight (g/mol): 173.212
• InChI Key: SEYCKMQSPUVYEF-LURJTMIESA-N
• Synonym: sch-50911 free base, unii-13ob0keu61, 2s-5,5-dimethylmorpholin-2-yl acetic acid, dsstox_cid_25670, dsstox_rid_81045, 2s-+-5,5-dimethyl-2-morpholineacetic acid, dsstox_gsid_45670, 2-2s-5,5-dimethylmorpholin-2-yl acetic acid, spectrum_001764, sch 50911 free base
• PubChem CID: 5311429
• IUPAC Name: 2-[(2S)-5,5-dimethylmorpholin-2-yl]acetic acid
• SMILES: CC1(COC(CN1)CC(=O)O)C

• Quantity: 10 mg
• Formula Weight: 173.21
• Percent Purity: >98%
• Chemical Name or Material: SCH 50911