Tocris Bioscience™ SecinH3

Sec7-specific GEF inhibitor; selective for cytohesin family

Brand:  Tocris Bioscience™ 2849/5

Product Code. 18034292

Description

SecinH3 is a Sec7-specific GEF inhibitor that displays selectivity for small GEFs of the cytohesin family (IC50 values are 2.4, 5.4, 5.4, 5.6, 5.6, 65 and > 100 μM for hCyh2, hCyh1, mCyh3, hCyh3, drosophila steppke, yGea2-S7 and hEFA6-S7 respectively). Inhibits insulin signaling via inhibition of insulin receptor substrate protein (IRS) phosphorylation.

Specifications

• Chemical Name or Material: N-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide
• Quantity: 5 mg
• Molecular Formula: C₂₄H₂₀N₄O₄S

• CAS: 853625-60-2
• Target: ARF GTPase Inhibitors
• Purity: 98%