SIRT6 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA116956

Product Code. 11511822

Description

PA1-16956 is specific for the ∽39 kDa SIRT6 protein. A higher molecular weight band at ∽59 kDa may be seen with lower dilutions such as 2 μg/mL.

Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human aging.

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Specifications

• Antigen: SIRT6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIRT6
• Gene Alias: 2810449N18Rik; AI043036; NAD-dependent deacetylase sirtuin-6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; SIR2; SIR2 like 6; Sir2l6; SIR2-like protein 6; sir2-related protein type 6; Sirt6; sirtuin 6; sirtuin type 6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51548
• Content And Storage: 4° C, do not freeze
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: phosphate, tris citrate with 0.1% sodium azide; pH 7-8
• Gene Accession No.: Q8N6T7
• Gene Symbols: SIRT6
• Immunogen: Synthetic peptide between amino acids 250-350 of the human SIRT6 protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG