Tocris Bioscience™ SJ 1008066

MAGE-A11 inhibitor disrupts MAGE-A11:PCF11 interaction

Brand:  Tocris Bioscience™ 7542/5

Product Code. 18075252

Description

SJ 1008066 is a cell permeable inhibitor of testis-restricted melanoma antigen protein MAGE-A11 (IC50 = 0.13 μM). SJ 1008066 binds to the MAGE homology domain (MHD) and disrupts MAGE-A11:PCF11 interaction. SJ1008066 exhibits no effect on MAGE-A3:AMPKα1 or MAGE-F1:MMS19 interactions in TR-FRET and cell lysate pulldown assays.

Specifications

• Chemical Name or Material: N1-((1 H-Indol-5-yl)methyl)-N3-(quinolin-4-yl)propane-1,3-diamine
• Target: Ubiquitin Ligase (E3) Inhibitors
• Purity: 98%

• Quantity: 5 mg
• Molecular Formula: C₂₁H₂₂N₄