SMARCB1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5143370

Product Code. 17870756

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial. Positive control: adult zebrafish.

The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2alpha) and Brg-1 (also designated SNF2beta) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).

Specifications

• Antigen: SMARCB1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: smarcb1a
• Gene Alias: AU020204; Baf47; BRG1-associated factor 47; BRG1-associated factor 47 (BAF47); CSS3; hSNF5; hSNFS; INI1; Integrase interactor 1 protein; malignant rhabdoid tumor suppressor; MRD15; mSNF5; PPP1R144; protein phosphatase 1, regulatory subunit 144; RDT; RTPS1; Sfh1p; SMARCB1; smarcb1a; SNF5; SNF5 homolog; SNF5/INI1; SNF5L1; Snr1; Sucrose nonfermenting yeast homolog like 1; sucrose nonfermenting, yeast, homolog-like 1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 isoform a; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1-A; SWI/SNF-related matrix-associated protein; SWI10; SWNTS1; Transcription factor TYE
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 799716
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q5U379
• Gene Symbols: smarcb1a
• Immunogen: The immunogen used to generate this antibody corresponds to zebrafish Smarcb1a
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Zebrafish
• Product Type: Antibody
• Isotype: IgG