Thermo Scientific™ SMART Digest™ Trypsin Kits

Product Code	Brand	Description	Format	Includes
15382360	Thermo Scientific™ 60109-101	SMART Digest Trypsin Kit, with Collection plate	SMART Digest Resin Pre-filled into PCR Tubes	SMART Digest Resin Pre-filled into 96 PCR Tubes, Collection Plate
16434839	Thermo Scientific™ 60109-101-B-LPH	Smart digest kit with bulk resin , low pH	SMART Digest Low pH Resin Pre-filled into PCR Tubes	SMART Digest Low pH Resin Pre-filled into 96 PCR Tubes, Collection Plate
15994417	Thermo Scientific™ 60109-101-LPH	Smart digest kit with collection plate, low pH	SMART Digest Low pH Resin Pre-filled into PCR Tubes	SMART Digest Low pH Resin Pre-filled into 96 PCR Tubes, Collection Plate
15317298	Thermo Scientific™ 60109-103	SMART Digest Trypsin Kit, with SOLAμ/collection plate	SMART Digest Resin Pre-filled into PCR Tubes	SMART Digest Resin Pre-filled into 96 PCR Tubes, Collection Plate, SOLAμ SPE Plate
16444839	Thermo Scientific™ 60109-101-MB-LPH	Smart digest kit, magnectic bead, bulk, low pH	SMART Digest Low pH Resin Pre-filled into PCR Tubes	SMART Digest Low pH Resin Pre-filled into 96 PCR Tubes, Collection Plate
15357350	Thermo Scientific™ 60109-102	SMART Digest Trypsin Kit, with Filter/Collection plate	SMART Digest Resin Pre-filled into PCR Tubes	SMART Digest Resin Pre-filled into 96 PCR Tubes, Collection Plate, Filter Plate
30130374	Thermo Scientific™ 60113-101-LPH	Soluble smart digest kit, trypsin, low pH buffer	SMART Digest Low pH Buffer	SMART Digest Low pH Buffer
15648663	Thermo Scientific™ 60109-101-B	SMART Digest Trypsin Kit, Magnetic Bulk Resin option	SMART Digest Resin, Bulk Magnetic	Bulk Magnetic SMART Digest Resin, SMART Digest Buffer
15791377	Thermo Scientific™ 60109-101-MB	SMART Digest Trypsin Kit, Magnetic Bulk Resin option	SMART Digest Resin, Bulk Magnetic	Bulk Magnetic SMART Digest Resin, SMART Digest Buffer
15658663	Thermo Scientific™ 60109-102-B	SMART Digest Trypsin Kit, Bulk Resin option with Filter/Collection plate	SMART Digest Resin, Bulk Non-magnetic	Bulk Non-magnetic SMART Digest Resin, SMART Digest Buffer, Collection Plate, Filter Plate
15668663	Thermo Scientific™ 60109-102-MB	SMART Digest Trypsin Kit, Magnetic Bulk Resin option with Filter/Collection plate	SMART Digest Resin, Bulk Magnetic	Bulk Magnetic SMART Digest Resin, SMART Digest Buffer, Collection Plate, Filter Plate
15678663	Thermo Scientific™ 60109-103-B	SMART Digest Trypsin Kit, Bulk Resin option with SOLAμ/collection plate	SMART Digest Resin, Bulk Non-magnetic	Bulk Non-magnetic SMART Digest Resin, SMART Digest Buffer, Collection Plate, SOLAμ SPE Plate
15668693	Thermo Scientific™ 60113-101	SMART Digest Trypsin Kit, Soluble	SMART Digest Soluble Trypsin	SMART Digest Soluble Trypsin, SMART Digest Buffer, Collection Plate
15688663	Thermo Scientific™ 60109-103-MB	SMART Digest Trypsin Kit Magnetic Bulk Resin option with SOLAμ/collection plate	SMART Digest Resin, Bulk Magnetic	Bulk Magnetic SMART Digest Resin, SMART Digest Buffer, Collection Plate, SOLAμ SPE Plate

Description

Obtain high quality analytical results from protein digests using Thermo Scientific™ SMART Digest™ Kits. A significant advance in sample preparation for biopharmaceutical protein research, the kits provide fast and simple protein digestion with high reproducibility, high sensitivity, and high levels of data quality in a format that's compatible with automation. The SMART Digest Kits are a significant improvement over current in-solution protein digestion technologies, which are not reproducible, have poor sensitivity, and employ protracted methodologies not amenable to automation.

Trypsin Protein Digestion

SMART Digest kits enable you to characterize and quantitate proteins faster, easier, and quicker than ever before. This version of the kit uses trypsin, which cleaves peptides on the C-terminal side of lysine and arginine amino acid residues.

Easy and simple

• Significantly increased speed of sample processing
• Simple process
• Easily automate entire protocol for high-throughput processing

Reliable Results

• Increased reproducibility over existing protocols
• Higher sensitivity
• Higher data confidence

Significantly Reduces Sample Preparation Time

Typically it takes less than 60 minutes (dependent on sample complexity) to achieve full digestion, whereas an in-solution digest can take up to 24 hours.

Cleaner Samples

Reduction in the number of chemicals used and the immobilized trypsin design helps mitigate against chemically induced post translational modifications (PTMs) and autolysis. This results in results which are easier to interpret.

Couple with SOLAμ SPE Plates for Desalting

When used with the SMART Digest kits for desalting, Thermo Scientific™ SOLAμ™ SPE solid phase extraction plates provide a fast, easy-to-use, robust, and easily automatable sample preparation solution for analysis of biomolecules.

Specifications

• For Use With (Application): Peptide Quantitation, Peptide Mapping

Safety and Handling

Product Identifier

• Trypsin Kits

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2

Hazard Statement

• H319-Causes serious eye irritation.

Precautionary Statement

• P264-Wash hands thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : sodium azide, calcium chloride