SOD3 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Código de producto	Marca	Quantity
16892894	Proteintech 14316-1-AP-20UL	20 μL
16882894	Proteintech 14316-1-AP-150UL	150 μL

Descripción

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.

Especificaciones

• Antigen: SOD3
• Applications: Western Blot, Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: P08294
• Gene ID (Entrez): 6649
• Immunogen: SOD3 Fusion Protein Ag5556
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SOD3

• Concentration: 0.29 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: EC SOD, Extracellular superoxide dismutase, SOD3, Superoxide Dismutase 3
• Gene Symbols: SOD3
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody