Sodium bis(trimethylsilyl)amide, 1M soln. in THF, Thermo Scientific Chemicals

Description

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Sodium bis(trimethylsilyl)amide is useful for the generation of carbenes, the amination of sulfonamides, and for the preparation of lanthanide complexes. It is significantly accelerated the polymerization of pheneylacetylene in conjunction with rhodium (I) catalysis. It is used to deprotonate ketones and esters to generate enolate derivatives, phosphonium salts, generating Wittig reagents.

Solubility
Soluble in benzene, toluene and ether. Reacts with water.

Notes
Moisture Sensitive. Incompatible materials are Oxidizing agents, Oxygen. Store away from water and oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 1070-89-9
• Molecular Formula: C6H18NNaSi2
• Molecular Weight (g/mol): 183.377
• MDL Number: MFCD00009835
• InChI Key: WRIKHQLVHPKCJU-UHFFFAOYSA-N
• Synonym: sodium bis trimethylsilyl amide, n-sodiohexamethyldisilazane, sodium hexamethyldisilazide, nahmds, sodiobis trimethylsilyl amine, sodium bis trimethylsilyl azanide, n-sodium hexamethyldisilazane, sodium-bis trimethylsilyl amide, hexamethyldisilazane sodium salt
• PubChem CID: 2724254
• IUPAC Name: sodium;bis(trimethylsilyl)azanide
• SMILES: C[Si](C)(C)[N-][Si](C)(C)C.[Na+]

• Quantity: 500 mL
• UN Number: UN2924
• Beilstein: 3629917
• Flash Point: −17°C (1°F)
• Solubility Information: Soluble in benzene,toluene and ether. Reacts with water.
• Formula Weight: 183.38
• Concentration or Composition (by Analyte or Components): 1M soln. in THF
• Sensitivity: Moisture sensitive; May form a precipitate
• Density: 0.904
• Chemical Name or Material: Sodium bis(trimethylsilyl)amide

Safety and Handling

Product Identifier

• Sodium bis(trimethylsilyl)amide, 1M solution in THF

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 4
• Carcinogenicity Category 2
• Serious eye damage/eye irritation Category 1
• Flammable liquid Category 2
• Skin corrosion/irritation Category 1 B
• Specific target organ toxicity Category 3

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H302-Harmful if swallowed.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.
• H335-May cause respiratory irritation.
• H336-May cause drowsiness or dizziness.
• H351-Suspected of causing cancer.
• EUH014-Reacts violently with water.
• EUH019-May form explosive peroxides.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : Tetrahydrofuran, Sodium bis(trimethylsilyl)amide

RUO – Research Use Only