Sodium ethoxide, 96%, Thermo Scientific Chemicals

Description

Sodium ethoxide is used as a strong base in organic synthesis. It is actively involved in the Claisen condensation, Stobbe reaction and Wolf-kishner reduction. It is an important starting material for the synthesis of ethyl ester and diethyl ester of malonic acid. In Williamson ether synthesis, it reacts with ethyl bromide to form diethyl ether. It is widely used as a base for the generation of carbanions which are utilized for alkylation and condensation reactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Sodium ethoxide is used as a strong base in organic synthesis. It is actively involved in the Claisen condensation, Stobbe reaction and Wolf-kishner reduction. It is an important starting material for the synthesis of ethyl ester and diethyl ester of malonic acid. In Williamson ether synthesis, it reacts with ethyl bromide to form diethyl ether. It is widely used as a base for the generation of carbanions which are utilized for alkylation and condensation reactions.

Solubility
Soluble in ethanol and methanol.

Notes
Moisture sensitive. It undergoes hydrolysis rapidly to form sodium hydroxide in the presence of moist air. Incompatible with water, strong bases, acids, oxidizing agents, alkali metals, strong oxidizing agents, ammonia, acid chlorides, acid anhydrides, reducing agents, peroxides, acids and chlorinated solvents.

Specifications

Chemical Identifiers

• CAS: 141-52-6
• Molecular Formula: C2H5NaO
• Molecular Weight (g/mol): 68.051
• MDL Number: MFCD00012417
• InChI Key: QDRKDTQENPPHOJ-UHFFFAOYSA-N
• Synonym: sodium ethoxide, sodium ethylate, sodium ethanolate, sodiumethoxide, ethoxysodium, ethanol, sodium salt, caustic alcohol, naoet, etona, ethanol, sodium salt 1:1
• PubChem CID: 2723922
• ChEBI: CHEBI:52096
• IUPAC Name: sodium;ethanolate
• SMILES: CC[O-].[Na+]

• Melting Point: >300°C
• pH: 13
• Flash Point: 30°C (86°F)
• Odor: Irritating
• Quantity: 100 g
• UN Number: UN3206
• Beilstein: 3593646
• Sensitivity: Air and moisture sensitive
• Merck Index: 14,8613
• Solubility Information: Soluble in ethanol and methanol.
• Formula Weight: 68.05
• Percent Purity: 96%
• Chemical Name or Material: Sodium ethoxide

Safety and Handling

Product Identifier

• Sodium ethoxide

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 1
• Flammable solid Category 1
• Self-heating substance Category 1
• Skin corrosion/irritation Category 1 B

Hazard Statement

• H228-Flammable solid.
• H251-Self-heating: may catch fire.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.
• EUH014-Reacts violently with water.

Precautionary Statement

• P235+P410-Keep cool. Protect from sunlight.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : Ethanol, sodium salt

RUO – Research Use Only