SOX2 Mouse anti-Human, Mouse, Porcine, Clone: 4B9B10, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66411-1-IG-150UL

Product Code. 16828265

Description

This antibody is raised against an internal region of human SOX2.

SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintece in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.

Specifications

• Antigen: SOX2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P48431, P48432
• Gene Symbols: SOX2
• Immunogen: SOX2 Fusion Protein Ag13635
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Porcine
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: 4B9B10
• Conjugate: Unconjugated
• Gene: SOX2
• Gene Alias: ANOP3, MCOPS3, SOX2, Transcription factor SOX 2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 20674, 407739, 6657
• Content And Storage: -20°C
• Form: Liquid