Spermine, 97%, Thermo Scientific Chemicals

Description

Binds to the polyamine modulatory site of NMDA Spermine is essential for both normal and neoplastic tissue growth. It is involved in the modulation of calcium-dependent immune processes. It plays an important role in cellular proliferation and differentiation as well as inhibits neuronal nitric oxide synthase (nNOS).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Binds to the polyamine modulatory site of NMDA Spermine is essential for both normal and neoplastic tissue growth. It is involved in the modulation of calcium-dependent immune processes. It plays an important role in cellular proliferation and differentiation as well as inhibits neuronal nitric oxide synthase (nNOS).

Solubility
Soluble in chloroform, methanol, water and lower alcohols. Insoluble in ether, benzene and petroleum ether.

Notes
Air sensitive and hygroscopic. Store in a cool place. Incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 71-44-3
• Molecular Formula: C10H26N4
• Molecular Weight (g/mol): 202.35
• MDL Number: MFCD00008215
• InChI Key: PFNFFQXMRSDOHW-UHFFFAOYSA-N
• Synonym: spermine, gerontine, musculamine, neuridine, spermin, 4,9-diaza-1,12-dodecanediamine, diaminopropyltetramethylenediamine, n,n'-bis 3-aminopropyl-1,4-butanediamine, spermine, puriss, 1,4-butanediamine, n,n'-bis 3-aminopropyl
• PubChem CID: 1103
• ChEBI: CHEBI:15746
• IUPAC Name: N,N'-bis(3-aminopropyl)butane-1,4-diamine
• SMILES: NCCCNCCCCNCCCN

• Melting Point: 28°C to 30°C
• Boiling Point: 150°C (5 mmHg)
• Flash Point: >110°C (230°F)
• Quantity: 1 g
• UN Number: UN3259
• Beilstein: 1751791
• Sensitivity: Air sensitive; Hygroscopic
• Merck Index: 14,8743
• Solubility Information: Soluble in chloroform,methanol,water and lower alcohols. Insoluble in ether,benzene and petroleum ether.
• Formula Weight: 202.35
• Percent Purity: 97%
• Chemical Name or Material: Spermine

Safety and Handling

Product Identifier

• Spermine

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 B

Hazard Statement

• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.

Precautionary Statement

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P264-Wash face, hands and anyexposed skin thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : Spermine

RUO – Research Use Only