Spermine tetrahydrochloride, 99%, Thermo Scientific Chemicals

Description

Binds to the polyamine modulatory site of NMDA

Spermine tetrahydrochloride, is used to precipitate DNA from low salt aqueous buffers. Spermine tetrahydrochloride was used to precipitate DNA for flow cytometric analysis from fresh frozen breast cancer tissue, archival tissue of salivary gland, renal and thyroid tumors2 and red blood cells of chicken.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Spermine tetrahydrochloride, is used to precipitate DNA from low salt aqueous buffers. Spermine tetrahydrochloride was used to precipitate DNA for flow cytometric analysis from fresh frozen breast cancer tissue, archival tissue of salivary gland, renal and thyroid tumors2 and red blood cells of chicken.

Solubility
Soluble in water (348.2 g/L at 20°C).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Hygroscopic. Store under inert gas. Keep away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 306-67-2
• Molecular Formula: C10H30Cl4N4
• Molecular Weight (g/mol): 348.18
• MDL Number: MFCD00012914
• InChI Key: XLDKUDAXZWHPFH-UHFFFAOYSA-N
• Synonym: spermine tetrahydrochloride, n,n'-bis 3-aminopropyl-1,4-butanediamine tetrahydrochloride, gerontine tetrahydrochloride, neuridine tetrahydrochloride, n1,n1'-butane-1,4-diyl bis propane-1,3-diamine tetrahydrochloride, musculamine tetrahydrochloride, geontine tetrahydrochloride, spermine hcl, 1,4-butanediamine, n,n'-bis 3-aminopropyl-, tetrahydrochloride, spermine, tetrahydrochloride
• PubChem CID: 9384
• IUPAC Name: N,N'-bis(3-aminopropyl)butane-1,4-diamine;tetrahydrochloride
• SMILES: [H+].[H+].[H+].[H+].[Cl-].[Cl-].[Cl-].[Cl-].NCCCNCCCCNCCCN

• Color: White
• Quantity: 5 g
• Beilstein: 3911771
• Solubility Information: Soluble in water (348.2g/L at 20°C).
• Formula Weight: 348.19
• Percent Purity: 99%
• Physical Form: Powder
• Chemical Name or Material: Spermine tetrahydrochloride

Safety and Handling

Product Identifier

• Spermine tetrahydrochloride

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.
• P332+P313-If skin irritation occurs: Get medical advice/attention.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : Spermine tetrahydrochloride

RUO – Research Use Only