Staurosporine, 99+%, Thermo Scientific Chemicals

Product Code. 15485139

Brand: Thermo Scientific Alfa Aesar J62837.#0

Descripción

Staurosporine (staurosporin, CAS # 62996-74-1) is a bacterial alkyloid isolated from Streptomyces staurosporeus.

Broad spectrum protein kinase inhibitor Staurosporine is used as anti-fungal and anti-hypertensive, which results to study the anti-cancer treatment. It acts as a precursor to protein kinase inhibitor midostaurin. It is also used to induce cell death in Swiss Webster primary macrophage cells and to study the effect of caspase activation on human sperm quality.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Staurosporine is an indolocarbazole alkaloid capable of permeating cell membranes
• Staurosporine has anti-cancer properties that can induce apoptosis
• Staurosporine is a broad inhibitor of protein kinases, preventing growth and division cycles

Application

• Staurosporine is used for research on acute myeloid leukemia
• It is suitable for research applications including cell culture and biochemistry

Especificaciones

Identificadores de productos químicos

• CAS: 62996-74-1
• Molecular Formula: C28H26N4O3
• Molecular Weight (g/mol): 466.541
• MDL Number: MFCD00077402
• InChI Key: HKSZLNNOFSGOKW-ZYSRIHRCSA-N
• Synonym: Antibiotic AM-2282
• PubChem CID: 49831000
• SMILES: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC

• Type: Staurosporine
• Physical Form: Powder
• Melting Point: 240°C to 243°C
• Color: Yellow
• Quantity: 5 mg
• Beilstein: 1060573
• Merck Index: 14,8802
• Solubility Information: Soluble in DMSO or ethanol;Soluble in dimethyl sulfoxide ,dimethyl formamide,ethyl acetate,hot acetone and ethanol; Slightly soluble in chloroform and methanol; Insoluble in water.
• Formula Weight: 466.54
• Percent Purity: ≥99%
• Chemical Name or Material: Staurosporine

Seguridad y manipulación

Nombre del producto

• Staurosporine

Palabra de advertencia

• Warning

Clasificación

• Carcinogenicity Category 2

Indicaciones de peligro

• H351-Suspected of causing cancer.

Consejos de prudencia

• P201-Obtain special instructions before use.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P308+P313-IF exposed or concerned: Get medical advice/attention.

Otros peligros

• MIXTURE LIST-Contains : Staurosporine

SDS

RUO – Research Use Only