SU 5416, Tocris Bioscience™

Description

VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3

Inhibitor of vascular endothelial growth factor receptor (VEGFR) that also inhibits other tyrosine kinases KIT, MET, FLT3 and RET. Displays no activity against EGFR, HER2, IGF1R and PDGFR. Inhibits tumor vascularization and growth of multiple tumor types.

Specifications

Chemical Identifiers

• CAS: 204005-46-9
• Molecular Formula: C15H14N2O
• Molecular Weight (g/mol): 238.29
• InChI Key: WUWDLXZGHZSWQZ-WQLSENKSSA-N
• Synonym: semaxanib, semaxinib, semoxind, semaxanib su5416, semaxnib, tsu 16, unii-71ia9s35aj, vegf receptor 2 kinase inhibitor iii, tsu-16, semaxanib usan/inn
• PubChem CID: 5329098
• IUPAC Name: (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one
• SMILES: CC1=CC(=C(N1)C=C2C3=CC=CC=C3NC2=O)C

• Quantity: 50 mg
• Formula Weight: 238.28
• Percent Purity: >99%
• Chemical Name or Material: SU 5416