Thermo Scientific Chemicals Sulfanilamide 98%

Description

Sulfanilamide, CAS # 63-74-1, is an organic sulfur compound that shows antibacterial activities.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Sulfanilamide is an organic sulfur compound with antibacterial properties that are structurally similar to the p-aminobenzoic acid (PABA)
• It also has a competitive inhibitory capacity against dihydropteroate synthetases blocking the synthesis of folic acid
• Sulfanilamide competes with PABA for the bacterial enzyme dihydropteroate synthase preventing, the incorporation of PABA into dihydrofolic acid, an immediate precursor of folic acid. This culminates in the inhibition of the bacterial folic acid synthesis and also the de novo synthesis of purines and pyrimidines, resulting in cell growth arrest and cell death.

Applications

• This compound shows antibacterial activity against different species, including gram-positive, gram-negative, and Chlamydia
• In chemical reactions, this compound can act as an intermediate for the preparation of 2,6-disubstituted anilines by electrophilic substitution
• Sulfanilamide shows inhibitory activity against the enzyme, carbonic anhydrase.

Specifications

Chemical Identifiers

• CAS: 63-74-1
• Molecular Formula: C6H8N2O2S
• Molecular Weight (g/mol): 172.202
• MDL Number: MFCD00007939
• InChI Key: FDDDEECHVMSUSB-UHFFFAOYSA-N
• Synonym: 4-Aminobenzenesulfonamide
• PubChem CID: 5333
• ChEBI: CHEBI:45373
• IUPAC Name: 4-aminobenzenesulfonamide
• SMILES: C1=CC(=CC=C1N)S(=O)(=O)N

• Type: Sulfanilamide
• Physical Form: Crystalline Powder
• Melting Point: 163.0°C to 167.0°C
• Infrared Spectrum: Authentic
• Loss on Drying: 0.5% max. (1 g, 105°C)
• Packaging: Plastic Bottle
• Color: White
• Quantity: 500 g
• Assay Percent Range: 98%
• Linear Formula: 4-(H₂N)C₆H₄SO₂NH₂
• Beilstein: 14, 698
• Merck Index: 15, 9057
• Solubility Information: Solubility in water: 7.5g/L (20°C).
• Formula Weight: 172.2
• Percent Purity: 98%
• Chemical Name or Material: Sulfanilamide, 98%

Safety and Handling

Product Identifier

• Sulfanilamide

Signal Word

• Warning

Hazard Category

• Skin corrosion/irritation Category 2
• Serious eye damage/eye irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P302+P352-IF ON SKIN: Wash with plenty of water/.
• P337+P313-If eye irritation persists: Get medical advice/attention.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P332+P313-If skin irritation occurs: Get medical advice/attention.

RUO – Research Use Only