Thermo Scientific™ SurePac™ Bio 550 SEC MDi™ HPLC Columns

Experience the future of Size-Exclusion Chromatography (SEC) with SurePac™ Bio 550 SEC MDi™ analytical columns and guards exclusively designed to deliver robust and reproducible performance at high resolution and throughput to accelerate your therapeutics analysis process.

Product Code	Brand	Length (Metric)	Diameter (Metric)	Column Format	Flow Rate
18415672	Thermo Scientific™ 43903-152131	150 mm	2.1 mm	Analytical Column	125 μL/min.
18425672	Thermo Scientific™ 43903-154631	150 mm	4.6 mm	Analytical Column	0.6 mL/min.
18405672	Thermo Scientific™ 43903-157831	150 mm	7.8 mm	Analytical Column	1.0 mL/min.
18435672	Thermo Scientific™ 43903-032131	30 mm	2.1 mm	Guard Column	125 μL/min.
18455672	Thermo Scientific™ 43903-034631	30 mm	4.6 mm	Guard Column	0.6 mL/min.
18445672	Thermo Scientific™ 43903-037831	30 mm	7.8 mm	Guard Column	1.0 mL/min.

Description

Experience the future of Size-Exclusion Chromatography (SEC) with SurePac™ Bio 550 SEC MDi™ analytical columns and guards exclusively designed to deliver robust and reproducible performance at high resolution and throughput to accelerate your therapeutics analysis process. The column's groundbreaking MDi™ technology integrates our advanced 3 μm monodisperse silica particle platform with bioinert hardware to ensure superior reliability for best sample recovery. SurePac™ Bio 550 SEC MDi™ column is ideal for AAV gene therapeutics analysis and offers excellent selectivity due to the dedicated smaller particle (3 μm) size combined with wide-pore (550Å) for separating monomeric AAVs from aggregates based on their size differences.

SurePac Bio 550 SEC MDi columns and guards are based on high-purity, spherical, porous (550 Å), 3 μm monodispersed silica particles that are covalently modified with a proprietary diol hydrophilic layer. This unique design yields shorter diffusion distances and enhanced reproducible mass transfer and narrower peaks. The consistent size of these particles facilitates precise control over media synthesis and column packing, significantly improving column-to-column and lot-to-lot reproducibility. The columns are housed in a hydrophilic bioinert-coated stainless-steel hardware to eliminate secondary interactions, ensuring optimal performance during the initial injection process.

• Ideal for AAV gene therapy characterization and quality control assessment due to selectivity of the dedicated smaller particle (3 μm) combined with wide-pore (550Å) size
• Superior column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing
• High-efficiency peaks with excellent recovery
• Higher resolution and throughput for fast turnaround time without sacrificing performance
• Bioinert hardware to eliminate analyte adsorption

Specifications

• Particle Size: 3 μm
• Quantity: 1 Ea.
• Stationary Phase: Proprietary
• Phase: Size Exclusion

• pH: 2 to 8
• Temperature: 20°C to 60°C
• Packing Material: Monodisperse Silica Resin
• Technique: SEC