Synaptophysin Monoclonal Antibody (7H12), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA515623

Product Code. 11315593

Description

MA5-15623 targets SYP in indirect ELISA, IHC and WB applications and shows reactivity with Human and Rat samples. The MA5-15623 immunogen is purified recombinant fragment of SYP expressed in E. Coli. MA5-15623 detects SYP which has a predicted molecular weight of approximately 33.8kDa.

Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.

Specifications

• Antigen: Synaptophysin
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: P07825, P08247, Q62277
• Gene Symbols: Syp
• Immunogen: Purified recombinant fragment of SYP expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 20977, 24804, 6855
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 7H12
• Conjugate: Unconjugated
• Gene: Syp
• Gene Alias: A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1