TC-I 2000, Tocris Bioscience™

Description

TRPM8 blocker

TRPM8 channel blocker. Inhibits icilin -induced TRPM8 channel activation in rTRPM8-expressing CHO cells (IC50 = 53 nM).

Specifications

Chemical Identifiers

• CAS: 1159996-20-9
• Molecular Formula: C23H18F4N2O
• Molecular Weight (g/mol): 414.404
• InChI Key: ADCDUDFEGFKKQH-UHFFFAOYSA-N
• Synonym: n-4-fluorophenyl-1-4-trifluoromethyl phenyl-3,4-dihydroisoquinoline-2 1h-carboxamide, n-4-fluorophenyl-3,4-dihydro-1-4-trifluoromethyl phenyl-2 1h-isoquinolinecarboxamide, n-4-fluorophenyl-1-4-trifluoromethyl phenyl-3,4-dihydro-1h-isoquinoline-2-carboxamide
• PubChem CID: 57326210
• IUPAC Name: N-(4-fluorophenyl)-1-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-isoquinoline-2-carboxamide
• SMILES: C1CN(C(C2=CC=CC=C21)C3=CC=C(C=C3)C(F)(F)F)C(=O)NC4=CC=C(C=C4)F

• Color: White
• Quantity: 50 mg
• Formula Weight: 414.4
• Percent Purity: >99%
• Physical Form: Solid
• Chemical Name or Material: TC-I 2000