tert-Butyl carbazate, 98+%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11429533	Thermo Scientific Alfa Aesar A12383.14	25 g
11439533	Thermo Scientific Alfa Aesar A12383.22	100 g
11449533	Thermo Scientific Alfa Aesar A12383.36	500 g

Description

tert-Butyl carbazate is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
tert-Butyl carbazate is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.

Solubility
Soluble in ethanol and methanol.

Notes
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.

Chemical Identifiers

• CAS: 870-46-2
• Molecular Weight (g/mol): 132.163
• InChI Key: DKACXUFSLUYRFU-UHFFFAOYSA-N
• PubChem CID: 70091
• SMILES: CC(C)(C)OC(=O)NN

• Molecular Formula: C5H12N2O2
• MDL Number: MFCD00007593
• Synonym: tert-butyl carbazate, tert-butyl hydrazinecarboxylate, t-butyl carbazate, hydrazinecarboxylic acid, 1,1-dimethylethyl ester, t-butylcarbazate, tert-butoxycarbonyl hydrazide, boc-hydrazide, boc-hydrazine, tert-butoxycarbonyl hydrazine, carbazic acid tert-butyl ester
• IUPAC Name: tert-butyl N-aminocarbamate

Specifications

• CAS: 870-46-2
• Boiling Point: 63°C to 65°C (0.1 mmHg)
• Molecular Formula: C5H12N2O2
• UN Number: UN1325
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in ethanol and methanol.
• SMILES: CC(C)(C)OC(=O)NN
• Molecular Weight (g/mol): 132.163
• Formula Weight: 132.16
• Chemical Name or Material: tert-Butyl carbazate

• Melting Point: 37°C to 41°C
• Flash Point: 91°C (195°F)
• MDL Number: MFCD00007593
• Beilstein: 1756967
• Synonym: tert-butyl carbazate, tert-butyl hydrazinecarboxylate, t-butyl carbazate, hydrazinecarboxylic acid, 1,1-dimethylethyl ester, t-butylcarbazate, tert-butoxycarbonyl hydrazide, boc-hydrazide, boc-hydrazine, tert-butoxycarbonyl hydrazine, carbazic acid tert-butyl ester
• InChI Key: DKACXUFSLUYRFU-UHFFFAOYSA-N
• IUPAC Name: tert-butyl N-aminocarbamate
• PubChem CID: 70091
• Percent Purity: ≥98%

Safety and Handling

GHS H Statement
H228
Flammable solid.

P210-P240-P241-P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P361-P363-P370+P378q-P501c

H228-H301+H311-H315-H319-H335

missing translation for 'dotInformation' : Hazard Class: 4.1; Packaging Group: II

missing translation for 'einecsNumber' : 212-795-3

missing translation for 'tsca' : Yes

Recommended Storage : Keep cold

RUO – Research Use Only