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Tocris Bioscience™ TFB-TBOA
High affinity EAAT1 and EAAT2 blocker
£152.72 - £296.59
Specifications
| Chemical Name or Material | (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid |
|---|---|
| CAS | 480439-73-4 |
| Assay Percent Range | >98% |
| Solubility | Soluble to 100mM in DMSO |
| Molecular Formula | C19H17F3N2O6 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18044592
|
Tocris Bioscience™
2532/1 |
1 mg |
£152.72
1mg |
Estimated Shipment: 31-07-2024 Log in to see stock. |
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|
18024272
|
Tocris Bioscience™
2532/10 |
10 mg |
£296.59
10mg |
Estimated Shipment: 27-08-2024 Log in to see stock. |
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Description
Potent and selective glial glutamate transporter EAAT1 and EAAT2 inhibitor (IC50 values are 17, 22 and 300 nM for EAAT2, EAAT1 and EAAT3 respectively). Has no effect on EAAT4 and EAAT5, or a wide range of neuronal receptors and transporters. Attenuates glutamate-stimulated intracellular Na+ elevation in astrocytes in vitro (IC50 = 43 nM). Induces severe convulsions in vivo.Specifications
| (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid | |
| >98% | |
| C19H17F3N2O6 |
| 480439-73-4 | |
| Soluble to 100mM in DMSO | |
| Observed MW: 426.35 |
For Research Use Only