TFM-4AS-1, Tocris Bioscience™

Description

Selective androgen receptor modulator (SARM)

Potent selective androgen receptor modulator (SARM) (IC50 = 30 nM). Steroidal compound. Exhibits limited effects on reproductive tissues and sebaceous glands; does not repress AP-1-sensitive MMP-1 reporter. Inhibits 5α-reductase type I and II (IC50 values are 2 and 3 nM respectively).

Specifications

Chemical Identifiers

• CAS: 188589-61-9
• Molecular Formula: C27H33F3N2O2
• Molecular Weight (g/mol): 474.568
• InChI Key: YFBLEKKYWFJKBP-HRVOXWHZSA-N
• Synonym: tfm-4as-1, 1s,3as,3bs,5ar,9ar,9bs,11as-6,9a,11a-trimethyl-7-oxo-n-2-trifluoromethyl phenyl-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1h-indeno 5,4-f quinoline-1-carboxamide
• PubChem CID: 90488882
• IUPAC Name: (1S,3aS,3bS,9aR,9bS,11aS)-6,9a,11a-trimethyl-7-oxo-N-[2-(trifluoromethyl)phenyl]-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinoline-1-carboxamide
• SMILES: CC12CCC3C(C1CCC2C(=O)NC4=CC=CC=C4C(F)(F)F)CCC5C3(C=CC(=O)N5C)C

• Quantity: 10 mg
• Formula Weight: 474.56
• Percent Purity: >98%
• Chemical Name or Material: TFM-4AS-1